Scientists have just announced a major breakthrough after a study found that vitamin D can help to mitigate heart damage caused by Covid mRNA “vaccines.”
The discovery was made by Dr. Hing Wai Tsang and his team at the University of Hong Kong’s Department of Pediatrics and Adolescent Medicine.
The results of the study were published in the Frontiers in Immunology journal.
They set out to investigate whether vitamin D plays a protective role against acute myocarditis following Covid mRNA vaccination.
Myocarditis is an inflation of the heart muscle.
The condition restricts the heart’s ability to pump blood and can cause cardiac arrest, strokes, blood clots, and sudden death.
The researchers’ hypothesis suggests that individuals with low vitamin D levels may be at higher risk for vaccine-related myocarditis.
This is due to excessive natural killer (NK) cell activation and inflammatory cytokine release.
If true, this would open a path for clinical intervention using vitamin D supplementation to prevent or mitigate this serious Covid mRNA “vaccine” side effect.
The study analyzed 60 cases of Covid mRNA vaccine-related myocarditis in adolescents aged between 12 and 17.
The patients were admitted to public hospitals in Hong Kong between July 2021 and June 2022.
Researchers assessed:
- Vitamin D levels via liquid chromatography-tandem mass spectrometry (LC-MS/MS).
- Immune profiles, measuring cytokines, NK cell activation (CD69+ expression), and genotyping for vitamin D-related genetic variants.
- Cardiac biomarkers, notably troponin T (cTnT), to assess the severity of myocarditis.
- Clinical presentations, including chest pain, ICU admission rates, and ECG/MRI abnormalities.
All cases were rigorously diagnosed per the Brighton Collaboration Case Definition for Myocarditis and Pericarditis.
First hypovitaminosis D was problematically common in myocarditis patients:
- 73.3% of patients had insufficient or deficient vitamin D levels.
- Those with lower vitamin D were more likely to present with chest pain (p=0.0215) and require ICU admission (p=0.062).
- A strong inverse correlation was found between vitamin D levels and troponin T (cTnT), indicating worse cardiac damage in patients with vitamin D deficiency (p=0.0099).
- Follow-up samples from recovered patients showed persistently low vitamin D levels, suggesting pre-existing vitamin D insufficiency rather than a consequence of myocarditis.
The study found that vitamin D deficiency was linked to hyperinflammatory cytokine profiles:
- Patients with low vitamin D had significantly higher levels of IL-1β, IL-8, IL-12, and IFN-γ—cytokines known to amplify NK cell activation and drive myocarditis.
- IL-4, a known NK cell inhibitor, was higher in patients with sufficient vitamin D, suggesting a potential protective mechanism.
NK cell activation was directly tied to vitamin D levels, the study found:
- Higher levels of CD69+ NK cells (a key marker of activation) were found in patients with myocarditis who had low vitamin D levels (p<0.0001).
- CD69+ NK cell expansion correlated strongly with chest pain, reinforcing the hypothesis that NK cell overactivation is a driving force behind mRNA vaccine-related myocarditis.
- Monocyte activation (HLA-DR+) was unrelated to vitamin D levels, confirming that the inflammatory response in myocarditis is NK-cell driven, not monocyte-mediated.
The researchers noted that it’s possible that genetic factors play a role in vitamin D deficiency:
- Patients with the GC rs4588T allele (linked to the GC2 vitamin D-binding protein isoform) had lower circulating vitamin D and were at greater risk of myocarditis.
- The GC1S isoform was protective, suggesting genetic predisposition plays a key role in vaccine-related myocarditis susceptibility.
70% of myocarditis cases happened after dose two of an mRNA injection, the study discovered.
This finding aligns with previous reports that immune priming from the first dose may lead to a stronger inflammatory response upon re-exposure.
30% of patients required ICU admission, which is an alarming rate for a vaccine side effect.
The researchers warn that this signals the potential severity of vaccine-related myocarditis in certain individuals.
This study breaks new ground by establishing a clear link between vitamin D deficiency, NK cell overactivation, and mRNA vaccine-related myocarditis.
The findings suggest vitamin D supplementation could be a simple way to mitigate the damage caused to the hearts of people who received Covid shots.
This study lays the foundation for future research and possible clinical interventions.
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